Blar i forfatter "Francis, Nick A"

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    • Antibiotic prescribing for acute Respiratory tract infections 12 months after communication and CRP training: a randomized trial 

      Little, Paul; Stuart, Beth; Francis, Nick A; Douglas, Elaine; Tonkin-Crine, Sarah; Anthierens, Sibyl; Cals, Jochen W L; Melbye, Hasse; Santer, Miriam; Moore, Michael; Coenen, Samuel; Butler, Christoffer C; Hood, Kerenza; Kelson, Mark; Godycki-Cwirko, Maciek; Mierzecki, Artur; Torres, Antoni; Llor, Carl; Davies, Melanie; Mullee, Mark; O'Reilly, Gilly; van der Velden, Alike; Geraghty, Adam; Goossens, Herman; Verheij, Theo; Yardley, Lucy (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03)
      <i>PURPOSE</i> - C-reactive-protein (CRP) is useful for diagnosis of lower respiratory tract infections (RTIs). A large international trial documented that Internet-based training in CRP point-of-care testing, in enhanced communication skills, or both reduced antibiotic prescribing at 3 months, with risk ratios (RRs) of 0.68, 0.53, 0.38, respectively. We report the longer-term impact in this ...

    • C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations 

      Butler, Christopher C; Gillespie, David; White, Patrick; Bates, Janine; lowe, rachel; Thomas-Jones, Emma; Wootton, Mandy; Hood, Kerenza; Phillips, Rhiannon; Melbye, Hasse; Llor, Carl; Cals, Jochen W L; Naik, Gurudutt; Kirby, Nigel; Gal, Micaela; Riga, Evgenia; Francis, Nick A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      <i>BACKGROUND</i> - Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD).<p><p> <i>METHODS</i> - We performed a multicenter, open-label, randomized, controlled trial involving patients with a diagnosis of COPD in their primary care clinical ...